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LONDON, ENGLAND, March 23, 2001: Have you always thought that by simply looking at a person’s face you could tell whether he or she is a smoker? Now there is scientific proof to back up your guess. A study conducted by Professor Antony Young at Guys, Kings and St. Thomas’ School of Medicine has shown that the skin of smokers contains high concentrations of a gene called MMP-1. Apparently this gene is responsible for the breakdown of collagen, a component of skin tissue that helps the organ retain its elasticity. Smoking activates this enzyme and skin turns wrinkly and grey.